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KMID : 0352720100340020145
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Journal of Ginseng Research
2010 Volume.34 No. 2 p.145 ~ p.149
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Protective Effects of Ginseng Coffee against Hydrogen Peroxide-induced Oxidative Damage in L6 Muscle Cells
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Lee Yeon-Mi
Kim Kyung-Tack
Bae Hye-Min
Lee Young-Chul
Choi Sang-Yoon
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Abstract
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This study investigated the antioxidant effects of ginseng coffee in L6 muscle cells. Ginseng coffee was prepared by coating and digesting coffee beans with ginseng concentrate. The ginseng coffee water extract potently protected against hydrogen peroxide-induced L6 cell death and adenosine triphosphate reduction in a dose-dependent manner; in fact, these cytoprotective effects were significantly greater than those of normal coffee. However, ginseng coffee did not exhibit significant radical scavenging or catalase-like activity. These results suggest that ginseng coffee might act as a cytoprotective agent in muscles, but that the protective effects are not due to a direct radical-reduction property but rather to another intracellular signaling factor.
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KEYWORD
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Ginseng, L6, Muscle cell, Antioxidant, Coffee
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